Boston Marriot Long Wharf | August 3-5, 2018
Program at a Glance
Event Schedule Subject to Change
7:00 AM
EXHIBITS AND CONTINENTAL BREAKFAST
8:00 AM
WELCOME AND INTRODUCTION
8:10 AM – 12:30 PM
SESSION I. PRECISION SCREENING AND DIAGNOSTIC ASSESSMENT FOR EARLY DETECTION OF CLINICALLY SIGNIFICANT PROSTATE CANCER
12:30 PM – 1:30 PM
LUNCH BREAK
1:30 PM – 6:30 PM
SESSION II. DIAGNOSTIC ASSESSMENT OF MEN WITH PROVEN LOCALIZED PROSTATE CANCER: Prediction of Progression, Staging, Patient Selection for Treatment and Post-Operative Assessment
7:00 PM
DINNER RECEPTION
7:30 PM
INDUSTRY LEADERSHIP SESSION ON ACCELERATING INNOVATION AND ADOPTION: Current Challenges and Solutions – Role of Technology Assessment, Clinical Guidelines and Reimbursement Policy
9:00 PM
POSTER SESSION
SUNDAY, AUGUST 5, 2018
7:00 AM – 8:00 AM
EXHIBITS AND CONTINENTAL BREAKFAST
8:00 AM – 9:30 AM
SESSION III: PRECISION DIAGNOSTICS AND EMERGING ROLE OF FOCAL TREATMENT
9:30 AM – 12:30 PM
SESSION IV: PRECISION ONCOLOGY FOR RECURRENT AND ADVANCED PROSTATE CANCER
12:30 PM – 1:30 PM
LUNCH BREAK
1:30 PM – 2:45 PM
SESSION V: SUMMARY PANEL DISCUSSION – Summit Highlights: Most Promising Current Clinical and Research Trends in Precision Screening, Diagnosis and Treatment and Expediting their Transfer from Laboratories to Patients
3:00 PM
BRAIN TRUST MEETING: Development of the Consensus Recommendations – Defining and Addressing Priority Needs in Precision Clinical Care by Designing Research, Medical Education and Training Programs
5:30 PM
ADJOURN
8:00 AM
WELCOME AND INTRODUCTION:
Faina Shtern, MD, President and CEO, AdMeTech Foundation
8:10 AM
SESSION I. PRECISION SCREENING AND DIAGNOSTIC ASSESSMENT FOR EARLY DETECTION OF CLINICALLY SIGNIFICANT PROSTATE CANCER
Moderators
Gerald Andriole, MD, Robert Royce Distinguished Professor, Chief of Urologic Surgery, and Vice-Chair, Department of Surgery, Washington University School of Medicine, Barnes-Jewish Hospital, and Member, National Comprehensive Cancer Network (NCCN)’s Prostate Cancer Early Detection Panel
Richard Babayan, MD, Professor and Chairman, Department of Urology, Boston University School of Medicine; and Chief of Urology, Boston Medical Center
Michael Blute, MD, Walter S. Kerr, Jr. Professor of Urology and Surgery, Harvard Medical School; and Chief of Urology, Massachusetts General Hospital
8:15 AM
State of the Art in “Smart” Prostate Cancer Screening: Defining the Need for Precision Diagnostics
Sigrid Carlsson, MD, PHD, MPH, Assistant Attending Epidemiologist, Department of Surgery (Urology Service), Memorial Sloan Kettering Cancer Center and Associate Professor of Experimental Urology, Sahlgrenska Academy, Gothenburg University, Sweden
8:30 AM
Q & A
8:35 AM
IsoPSA, a Novel Structure-Based Assay for Screening
Eric Klein, MD, Chairman, Glickman Urological and Kidney Institute, Cleveland Clinic
8:50 AM
Q & A
8:55 AM
A Way Forward in Early Detection Of Prostate Cancer: Integrating Liquid Molecular Markers
David Crawford, MD, E. David Crawford Distinguished Endowed Chair in Urology, University of Colorado, Denver
9:10 AM
Q & A
9:15 AM
Liquid Biopsy: Definition and Clinical Utility
Michael Donovan, MD, PhD, Professor of Pathology, Mount Sinai Medical Center
9:30 AM
Q & A
9:35 AM
Current and Emerging Imaging Tools for Improving Risk Assessment, Selection of Patients for Biopsy and Tissue Sampling
9:35 AM
Multi-Parametric (mp) Magnetic Resonance Imaging and PI-RADS for Risk Assessment Prior to Biopsy
Jeffrey Weinreb, MD, Professor and Vice Chair for Strategic Planning and Innovation, Department of Diagnostic Radiology and Biomedical Imaging,Yale School of Medicine
9:50 AM
mpMRI, PI-RADS and Multi-Modality Image Fusion for Target Definition and Tissue Sampling
Jelle Barentsz, MD, PhD, Chair and Professor of Radiology Prostate MR Center of Excellence, Nijmegen Medical Center, Radboud University, The Netherlands
10:05 AM
Q & A
10:10 AM – 10:30 AM
Coffee Break
10:30 AM
Real-time High Resolution Micro-Ultrasound for Targeted Biopsies – A Multi-Center Comparison to mpMRI
Sangeet Ghai, MD, Associate Professor, Department of Medical Imaging, University of Toronto, Canada
10:45 AM
Q & A
10:50 AM
Effectiveness and Economic Implications of Population-Level Adoption of MRI-Guided Prostate Biopsies
Christopher Filson, MD, Assistant Professor of Urology, Emory University
11:05 AM
NCCN Guidelines for Early Detection of Prostate Cancer
Preston Sprenkle, MD, Assistant Professor of Surgery, Yale University School of Medicine; and Member, NCCN Prostate Cancer Early Detection Panel
11:20 AM
Q & A
11:25 AM
Integration of In Vitro Diagnostics with In Vivo Imaging
Sanoj Punnen, MD, Assistant Professor of Surgery, University of Miami Miller School of Medicine
11:40 AM
Panel: Emerging Best Practices in Precision Screening and Diagnostic Assessment for Early Detection of Prostate Cancer
Moderators, Speakers and
Matthew Cooperberg, MD, MPH, Associate Professor, Department of Urology and Epidemiology Biostatistics, Helen Diller Family Chair in Urology, University of California, San Francisco
Kelvin Moses, MD, PhD, Assistant Professor of Urology, Department of Urologic Surgery, Vanderbilt University Medical Center, Chief of Urology, Nashville General Hospital, and Member, Vanderbilt-Ingram Cancer Center; and Member, NCCN Prostate Cancer Early Detection Panel
Peter Pinto, MD, Head of Prostate Cancer Section, Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health
Stephen Zappala, MD, Assistant Clinical Professor of Urology, Tufts University School of Medicine
12:30 PM – 1:30 PM
Lunch Break
1:30 PM
SESSION II. DIAGNOSTIC ASSESSMENT OF MEN WITH PROVEN LOCALIZED PROSTATE CANCER:
Prediction of Progression, Staging, Patient Selection for Treatment and Post-Operative Assessment
Moderators
David Crawford, MD, E. David Crawford Distinguished Endowed Chair in Urology, University of Colorado, Denver
Angelo DeMarzo, MD, PhD, Associate Professor of Pathology, Urology, Oncology, Johns Hopkins University School of Medicine
Eric Klein, MD, Chairman, Glickman Urological and Kidney Institute, Cleveland Clinic
1:35 PM
In Vivo Imaging
1:35 PM
Current Status of mpMRI and Multi-Modality Diagnostics – and Clinical Trial of the Eastern Cooperative Oncology Group and Amedical College of Radiology Imaging Network
Clare Tempany, MD,
Ferenc Jolesz, MD Professor of Radiology, Harvard Medical School; Vice Chair, Research Radiology, Brigham and Women’s Hospital; and Director, National Center for Image-Guided Therapy
1:50 PM
Q&A
1:55 PM
Radiomics and Machine Learning with Multiparametric Imaging
Masoom Haider, MD, Professor of Radiology and Vice Chair, Radiomics and Quantitative Imaging, University of Toronto, Canada
2:10 PM
Q&A
2:15 PM
Radiogenomics of Tumor Habitats – Addressing Prostate Cancer Heterogeneity:
Radka Stoyanova, PhD, Professor and Director, Imaging and Biomarkers Research, Department of Radiation Oncology and Associate Member, Sylvester Comprehensive Cancer Center, Miller School of Medicine University of Miami
2:30 PM
Q&A
2:35 PM
Tissue-Based Pathologic Assessment, Genomics and Phenotypic Biomarkers
2:35 PM
Anatomic Pathology
Thomas Wheeler, MD, Chairman and Professor of Pathology, Baylor College of Medicine
2:50 PM
Molecular Pathology
Angelo DeMarzo, MD, PhD, Associate Professor of Pathology, Urology, Oncology, Johns Hopkins University School of Medicine
3:05 PM
Q&A
3:10 PM
Genetic Cancer Profiling
Eric Klein, MD, Chairman, Glickman Urological and Kidney Institute, Cleveland Clinic
3:25 PM
Q&A
3:30 PM
Phenotypic Biomarkers and Precision Oncology
David Albala, MD, Chief of Urology, Crouse Hospital in Syracuse, New York; and Medical Director for Associated Medical Professionals
3:45 PM
Surrogate Outcomes
Jennifer Rider, ScD, MPH, Assistant Professor, Department of Epidemiology, Boston University School of Public Health
4:00 PM
Q&A
4:05 PM
Coffee Break
4:25 PM
Emerging Trends in Prostate Cancer Care: Impact of Precision Diagnostics
Matthew Cooperberg, MD, MPH
4:40 PM
Q&A
4:45 PM
Radiogenomics: Emerging and Future Impact on Treatment Selection and Monitoring
4:45 PM
Active Surveillance
Sanoj Punnen, MD
5:00 PM
Focal Treatment
Peter Pinto, MD
5:15 PM
Immediate Standard Whole Gland Treatment: Radical Prostatectomy and EBRT
Adam Feldman, MD, MPH, Assistant Professor of Surgery and Director of Combined Harvard Urology Oncology Fellowship, Massachusetts General Hospital, Harvard Medical School
5:30 PM
Q&A
5:40 PM – 6:30 PM
Panel on Diagnostic Evaluation of Men with Proven Localized Prostate Cancer and its Impact on Treatment Selection and Monitoring
Speakers, Moderators and Panel Members –
- Comments on Ultrasound and Multi-Modality Imaging – Sangeet Ghai, MD
- Comments on Improved Diagnosis of Clinically Significant PC – Susan Noworolski, PhD, Associate Professor, Department of Radiology, UCSF
- Comments on mpMRI for Cost-Effective Active Surveillance – Sejal Patel, MSc, Radboud University, The Netherlands
- Comments on Molecular Imaging – Heather Jacene, MD, Assistant Professor of Radiology and Associate Program Director, Brigham and Women’s Joint Program in Nuclear Medicine, Harvard Medical School
- Comments on Non-Invasive PSMA – Daniel Margolis, MD, Associate Professor of Radiology and Director, Prostate MRI and Abdominal Imaging, Weill Cornell Medicine
- Comments on Intraoperative Molecular Imaging for Staging – Wolfgang Weber, MD, Professor and Chair,Department of Nuclear Medicine, Klinikum rechts der Isar, Technical University of Munich, Germany
- Comments on Multi-Modality Novel Nomograms for Improved Risk Stratification – Amita Shukla-Dave, PhD, Deputy Service Chief for Predictive Informatics
7:00 pm
Dinner Reception
7:30 pm
Industry Leadership Session on Accelerating Innovation and Adoption:
Current Challenges and Solutions – Role of Technology Assessment, Clinical Guidelines and Reimbursement Policy
Moderators
Richard Frank, MD, PhD, Chief Medical Officer, Siemens Healthineers
Grannum R Sant, MD, FRCS, FACS, Professor and Former Chair of Urology, Tufts University School of Medicine; Former Head, Oncology/Urology Medical Affairs, Sanofi, and Rare Genetic Diseases, Genzyme
7:30 PM
Introduction: Four Hurdles to Adoption of Innovations into Clinical Practice
Richard Frank, MD, PhD
7:40 PM
mpMRI: Clinical Utilization and Health Economics
Heinrich von Busch, PhD, Product Owner, Artificial Intelligence for Oncology Imaging; and Artem Boltyenkov, PhD, Senior Manager, Global Health Economics and Outcomes Research, Siemens Healthineers
7:55 PM
PET/CT with Axumin (18F-fluciclovine): Clinical Implementation
Blue Earth Diagnostics: Jonathan Allis, PhD, CEO
8:10 PM
PET PSMA: Emerging Broad-Based Clinical Utility
Steven Rowe, MD, PhD, Assistant Professor of Radiology, Johns Hopkins University School of Medicine
8:15 PM
Improving Prostate Biopsy Guidance: Moving to 29 MHz Micro-Ultrasound
Brian Wodlinger, PhD, Manager, Advanced Development and Clinical Research, Exact Imaging
8:20 PM
In Vitro Diagnostics: Clinical Adoption
Kelvin Moses, MD, PhD
8:30 PM
Genomic Cancer Profiling: Clinical Role and Adoption
8:30 PM
Perspectives from Myriad Genetics
Brian Liu, PhD, Medical Science Liaison-Urology, Myriad Geneitcs
8:35 PM
Perspective from Genomic Health
Lisa Kaminsky, RN, BSN, CNOR, Sr. Medical Science Liaison
8:40 PM
Targeted Biopsy and Focal Treatment: Emerging Clinical Role
Antoine Leroy, President, Koelis
8:45 PM
Panel Discussion: Recommendations for Action to Accelerate Adoption
Moderators, Speakers and Peter Pinto, MD and Jeffrey Weinreb, MD
8:55 PM
Summary of Actions
Moderators: Richard Frank, MD, PhD and Grannum R. Sant, MD, FRCS, FACS
9:00 pm
Poster Session and Competition
8:00 AM
SESSION III: PRECISION DIAGNOSTICS AND EMERGING ROLE OF FOCAL TREATMENT
Moderators
Peter Pinto, MD, Head of Prostate Cancer Section, Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health
Mitchell Sokoloff, MD, Professor and Chair of Urology, University of Massachusetts School of Medicine
Clare Tempany, MD, Ferenc Jolesz MD Professor of Radiology, Harvard Medical School and Vice Chair for Radiology Research, Brigham and Women’s Hospital
8:05 AM
Multimodality Precision Diagnostics for Target Definition
8:05 AM
MRI/Ultrasound Fusion
Srinivas Vourganti, MD, Urologic Oncologist, Department of Urology and Assistant Professor, Rush University Medical Center
8:15 AM
Multi-Modality Imaging
Sadhna Verma, MD, MD, FSAR, Professor of Radiology, Director, Prostate Imaging Program, University of Cincinnati Cancer Institute and the Veterans Administration Hospital
8:25 AM
Radiogenomics
John Feller, MD, Founder, Desert Medical Imaging
8:35 AM
Q&A
8:40 AM
Overview of Patient Selection, Monitoring and Outcomes
8:40 AM
Radiology Perspective
Jurgen Futterer, MD, PhD, Interventional Radiologist, Nijmegen Medical Center and Professor, University of Twente, The Netherlands
8:55 AM
Urology Perspective: Clinical Trial Design and Gold Nanoparticle-Directed Focal Ablation
Art Rastinehad, DO, FACOS, Associate Professor of Urology and Radiology, and Director, Focal Therapy and Interventional Urology Program, Icahn School of Medicine at Mount Sinai Health System
9:10 AM
Panel Discussion: Moderators and Speakers
9:30 AM
SESSION IV: PRECISION ONCOLOGY FOR RECURRENT AND ADVANCED PROSTATE CANCER
Moderators
Angelo DeMarzo, MD, PhD, Associate Professor of Pathology, Urology, Oncology, Johns Hopkins University School of Medicine
Daniel Petrylak, MD, Professor of Medicine (Medical Oncology) and Urology; and Co-Director, Signal Transduction Research Program, Yale University Cancer Center
9:35 AM
Overview of Advanced Prostate Cancer, Including Oligometastatic Disease
Daniel Petrylak, MD
9:50 AM
Q&A
9:55 AM
Liquid Biopsy
David Nanus, MD, Mark W. Pasmantier Professor and Chief, Hematology and Oncology, New York-Presbyterian, and Director of Genitourinary Oncology, Weill Cornell Medicine
10:10 AM
Q&A
10:15 AM
Genomic Testing, including Germline Mutations
Angelo DeMarzo, MD, PhD
10:30 AM
Q&A
10:35 AM
Coffee Break
10:55 AM
Molecular and Multi-Modality Imaging
10:55 AM
Overview
Heather Jacene, MD, Assistant Professor of Radiology and Associate Program Director, Brigham and Women’s Joint Program in Nuclear Medicine, Harvard Medical School
11:10 AM
LOCATE Trial – Impact of PET with 18F-fluciclovine on Management of Patients with Suspected Recurrence
Gerald L. Andriole, MD
11:25 AM
Q&A
11:30 AM
PSMA PET: Steven Rowe, MD, PhD, Assistant Professor of Radiology, Johns Hopkins University School of Medicine
11:45 AM
PSMA Based Theranostics of Prostate Cancer
Wolfgang Weber, MD
12:00 PM
Q&A
12:05 PM
Panel Discussion
Moderators and Speakers
12:30 PM – 1:30 PM
Lunch
1:30 PM
SESSION V: SUMMARY PANEL DISCUSSION
Session Leaders
Gerald Andriole, MD, Matthew Cooperberg, MD, MPH, David Crawford, MD, Angelo Demarzo, MD, PhD, Masoom Haider, MD, Eric Klein, MD, Daniel Petrylak, MD, Peter Pinto, MD, Faina Shtern, MD, Clare Tempany, MD, and Wolfgang Weber, MD
1:30 PM
SUMMIT HIGHLIGHTS: Most Promising Current Clinical and Research Trends in Precision Screening, Diagnosis and Treatment and Expediting their Transfer from Laboratories to Patients
2:30 PM – 3:00 PM
Coffee Break
3:00 PM
BRAIN TRUST MEETING: Development of the Consensus Recommendations – Defining and Addressing Priority Needs in Precision Clinical Care by Designing Research, Medical Education and Training Programs
Discussion Leaders: Moderators, Speakers, Panelists
5:30 PM
ADJOURN